Database of Genotypes and Phenotypes (dbGaP)
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Summary
The Database of Genotypes and Phenotypes is a National Institutes of Health-sponsored repository charged to archive, curate and distribute information produced by studies investigating the interaction of genotype and phenotype. Information in dbGaP is organized as a hierarchical structure and includes the accessioned objects, phenotypes (as variables and datasets), various molecular assay data (SNP and Expression Array data, Sequence and Epigenomic marks), analyses and documents. Publicly accessible metadata about submitted studies, summary level data, and documents related to studies can be accessed freely on the dbGaP website. Individual-level data are accessible via Controlled Access application to scientists across the globe.
| Agency | HHS, NIH, NLM |
|---|---|
| Data Checkup |
Historical Data Availability
No Known Issue
Future Data Availability
No Known Issue
Data Quality
No Known Issue
Statutory Context
Moderate Risk
While not explicitly required by federal statute, submission to dbGaP is required under National Institutes of Health (NIH) policy. Specifically, all large-scale human genomic studies funded by the NIH must register and submit data to dbGaP under the NIH Genomic Data Sharing (GDS) policy.
Staffing and Funding
Moderate Risk
From FY2024 to FY2026, NIH has lost more than 4,000 staff (~20% of workforce).
Policy
No Known Issue
Last updated: 2026-07-16
Details
| OMB Control Number | 0925-0670 | |||
|---|---|---|---|---|
| Authorizing Statutes | 42 USC 241 sect. 301 | |||
| Related ICRs |
| Reference Number | Title | Agency | Status | Request Type |
|---|---|---|---|---|
| 202605-0925-004 | New NIH Information Collection Web Interface and Forms To Support Genomic Data Sharing and NIH Controlled-Access Data Repository Requirements (OD) | HHS/NIH | Active | No material or nonsubstantive change to a currently approved collection |
| 202508-0925-001 | NIH Information Collection Forms to Support Genomic Data Sharing for Research Purposes (OD) | HHS/NIH | Active | Revision of a currently approved collection |
| 202501-0925-001 | NIH Information Collection Forms to Support Genomic Data Sharing for Research Purposes (OD) | HHS/NIH | Historical Active | No material or nonsubstantive change to a currently approved collection |